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Williams Laboratory for Natural Product Synthetic Biology

gjwillia

Sep 24, 2023

Publication in ChemBioChem

I’m delighted to share our review article by graduate student Tad Paulsel on the chemoenzymatic synthesis of polyketides. Thanks to ChemBioChem for making this a VIP article and an Editors Choice Spotlight at ChemEurope.

Oct 6, 2021

Dr. Zhongtian Zhang

Huge congratulations to Zhongtian Zhang (aka Nemo) who passed his final defense! Dr. Zhang will soon begin work at Amyris. Nemo was a trainee of the Microbiology Graduate Program at NC State. His work involved the identification, characterization, and application of a novel CRISPR-Cas system. Ph.D. #14 for the Williams Group!

Sep 24, 2021

Biosensors for guiding engineering of macrolide biosynthesis

We are thrilled to share our latest work in developing biosensors for guiding macrolide biosynthesis! This is the product of an ongoing collaboration with Ashton Cropp’s group at VCU and was led by Williams Lab graduate student, Yiwei Li. This novel biosensor will allow us to search for and evolve novel enzymes for macrolide diversification.…

Apr 29, 2021

Teaching Award

Kudos to Tad Paulsel for being awarded the Department of Chemistry Anderson Award for Teaching!

Apr 29, 2021

Dr. Lexie Malico

Huge kudos to Lexie Malico who passed her final Ph.D. defense! Dr. Malico will begin work soon at BASF as part of their professional development program. Ph.D. #13 for the group! We wish her all the best in her future endeavors!

Apr 13, 2021

Publication in Nature Communications

We are thrilled to share our latest polyketide synthase engineering work by Edward Kalkreuter and our collaborators at the University of Michigan in Nature Communications. This work sets the stage to further diversify the structures of macrolides for drug development and discovery. See the NC State press release here.