Gavin Williams (PI) – Gavin received his B.Sc in Biochemistry (First Class Honors) from the University of Wales, and completed his PhD under the supervision of Dr Alan Berry at the University of Leeds. He then completed a postdoc at UW-Madison with Prof Jon Thorson, was appointed Assistant Professor at NC State in 2009, and promoted to Associate Professor in 2015. Gavin received the NSF CAREER Award inn 2013, was named a University Faculty Scholar (2015-2020) and received the Chancellor’s Innovation Award in 2016.
Current Graduate Students:
Samantha M. Carpenter – Sam received a BS in Chemistry from Lynchburg College in Lynchburg, Virginia. She joined the Williams Lab in the Fall of 2013 and is looking forward to using unnatural amino acid mutagenesis to probe and manipulate natural product biosynthesis.
Jared CroweTipton – Jared completed his BS in chemistry from Furman University in 2015 and joined the Williams lab in the fall of 2015. He is looking forward to probing and engineering polyketide synthases for the synthesis of new antibiotics.
Rachael Hall – Rachael completed her BS in Professional Chemistry and MS in Chemistry focusing on chemical education at Middle Tennessee State University. She joined the Williams Lab in the Fall of 2014 and is currently involved in research investigating polyketide and terpene biosynthetic pathways. She is currently supported by an NIH Molecular Biotechnology Training Fellowship.
Christian Kasey – Born and raised in Louisville, KY, Christian attended the University of Louisville (2013 NCAA Division 1 Mens basketball champions) and earned bachelors degrees in history and chemistry. He is now involved with the creation of biosensors for polyketide detection, and is developing an in vivo platform for polyketide diversification.
Robert (Edward) Kalkreuter – Edward graduated from Emory University with a BS in Chemistry. He joined the group in fall 2013 as a PhD candidate. His research interests include metabolic engineering of polyketide biosynthesis and developing ultra-higthroughput screening platforms.
Yiwei Li – Yiwei graduated from Beijing Normal University with a BS in Chemistry. She joined the group in fall 2014 as a PhD candidate. She is now involved with constructing biosensors for directed evolution, yeast cell surface display and riboswitch engineering.
Lexie Malico – Lexie graduated from Wesleyan University with a BA in Chemistry. She joined the Williams Lab in Fall 2016 and is interested in investigating polyketide biosynthetic pathways and natural product glycodiversification.
Lindsay Nichols – Lindsay received a B.S. in Biochemistry from Hope College in Holland, Michigan. She joined the Williams group in 2016 and is looking forward to developing biosensors for polyketides.
Undergraduate research assistants:
Katherine Almasy – Katherine is a Junior majoring in Chemistry. Katherine is a Goodnights Scholar and a Chancellors Leadership Scholar. She joins the polyketide diversification group.
Kyle Bingham – Kyle is a Park Scholar in the class of 2017. He is double majoring in Chemistry and Human Biology and is interested in engineering the ligand recognition properties of riboswitches. His research is funded by an NC State Office of Undergraduate Research Award.
Aaron Keeler – Aaron joined the lab in Spring 2017 as a Sophomore majoring in Chemistry.
Vishwas Rao – Vishwas joined the group in the Fall of 2013 as a Freshman Park Scholar double majoring in Chemistry and Biochemistry, with a minor in Music.
Mounir Zerrad – Mounir joined the group in the summer of 2014 and is majoring in Biomedical Engineering. His work involves fermentation scale synthesis of novel polyketide analogues and is funded by an Atlantic Coast Conference Inter-Institutional Academic Collaborative (ACCIAC) Fellowship.
Kimberley Castelli – Kim earned her B.S. in Biochemistry and Molecular Biology from NC State in 2012. After working in the pharmaceutical industry, Kim returned to NC State in 2014 to begin a Ph.D. in Chemistry. She looks forward to engineering polyketide synthases to diversify the structure of clinically relevant polyketides.
Taylor Courtney –Taylor joined the group in Fall 2013 as a Junior in Chemistry and Biochemistry. Her research was funded by an NC State Office of Undergraduate Research Award. Taylor won the Merck Award by the Department of Chemistry in recognition of her remarkable scholarly achievements at NC State and won the College of Science Outstanding Senior Award for Scholarship. She is now in the chemistry Ph.D. program at the University of Pittsburgh.
Hemant Desai – Hemant joined the group as an undergraduate research assistant in 2010. He graduated from NC State in 2013 with a double major in Chemistry and Biochemistry. Along the way he won the 2013 ACS Undergraduate Award in Organic Chemistry, the PAMS Senior Award for Scholarly Achievement, was the Highest Ranking student in College of PAMS, and was a recipient of an NCBC Undergraduate Research Fellowship. He is now in the M.D. program at UNC.
Matthew Draelos – Matthew graduated from NC State with a double major in Chemistry & Biochemistry, and a minor in Physics. Matthew was an NC State University Park Scholar, and recipient of the F. Ivy Carroll NC-ACS Undergraduate Scholarship Award. He won the Chemistry Outstanding Graduating Senior Award in the categories of Scholarly Achievement and Research. He also won the Biochemistry Undergraduate Horton Award for Excellence in Scholarship and Research.
Irina Koryakina – Irina obtained her BS in Pharmacy at the Perm State Pharmaceutical Academy in Russia, and graduated from NC State with a PhD in Chemistry in the Spring of 2014. Irina’s work focused on probing and engineering the extender unit promiscuity of type I polyketide synthases. She is now a postdoctoral research assistant in the group of Michael Toney at UC-Davis.
Chris Ladner – Chris graduated from Spring Hill College in Mobile, AL with a BS in Chemistry and Mathematics. He joined the group as a PhD candidate and is currently using directed evolution by yeast surface display to alter the specificity of natural product biosynthesis and to improve enzymes that site-selectively modify proteins. Chris also seems to like windmills.
Sean Lund – Sean studied chemistry at the University of California at Berkeley, and at the University of Minnesota, Twin Cities, where he received his BS in Chemistry. Sean joined the group in the Fall of 2012 and developed a novel in vitro and in vivo precursor-directed biosynthesis platform for terpene diversification. He was supported by a Department of Chemistry Graduate Fellowship. Sean is now a research scientist at Amyris, San Francisco Bay Area.
John McArthur – John completed his BS at the University of South Carolina and joined the group as a PhD candidate in 2009. John graduated with a PhD in the Fall of 2014, his research involved devising new methods for evolving novel enzymatic functions. John is now a postdoctoral research assistant in the group of Xi Chen at UC-Davis.
Jessica Neville – Jessica first joined the group as an REU student in the summer of 2010 and then was an undergraduate research assistant until 2012. She is now taking part in the M.D./Ph.D. program at the University of Maryland.
Phung Nguyen – Phung graduated with a BS in chemistry from Armstrong Atlantic State University in Savannah, GA, in 2012, and joined the group shortly after. Her research in the Williams group focused on using computational redesign to alter the specificity of unnatural extender unit incorporation in the biosynthesis of natural products by type III polyketide synthases. Phung is now an adjunct chemistry instructor at Savannah Technical College, Georgia.
Sarah Schultheis – Sarah graduated from the University of North Carolina Wilmington with a B.S. in Chemistry. She joined the Williams lab in Fall 2013 and graduated May 2015 with a Masters in Chemistry. She is now employed as a Senior Research Associate at Novozymes, North Carolina.
Steve Walsh – Born and raised in Massachusetts, Steve then took his talents to New York where he got a BE in chemical engineering from The Cooper Union. He graduated in May 2015 with a PhD and is now employed at BASF. Steve was also Time Magazine’s Person of the Year in 2006.
Zhixia Ye – Zhixia graduated from Beijing Institute of Technology with a BS in Chemistry and joined the Williams lab in fall 2009. She graduated from NC State with a PhD in Chemistry in the Spring of 2014 and is now a postdoctoral research fellow at Duke University. Her research focused on probing and manipulating protein-protein interactions in biosynthetic assembly lines.