Thrilled to share our latest review article, “Transcription factor-based biosensors: A molecular-guided approach for natural product engineering”, with Melissa Mitchler, Jessie Garcia, and Nichole Montero. Nice work everybody!
The Williams lab is excited to announce that we have been selected to receive a Chancellor’s Innovation Fund award to advance our genome engineering technology. Read more about it here.
Thrilled to share our review article on synthetic biology enabling access to designer polyketides with graduate students Alexandra Malico & Lindsay Nichols!
“Polyketide synthases are multi-domain enzymes that catalyze the construction of many bioactive natural products. Now, some of the inefficiencies and limitations of these systems have been solved by designing an artificial pathway for carbon–carbon bond formation via iterative rounds of non-decarboxylative thio-Claisen reactions.”